Evolution of the Muscarinic Acetylcholine Receptors in Vertebrates
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چکیده
منابع مشابه
The role of acetylcholine muscarinic receptors in the rat basolateral amygdala on morphine-induced place preference
Some studies have shown that acetylcholine muscarinic receptors involved in the opiate reward. In the present study, the effect of intra-basolateral amygdale (BLA) acetylcholine muscarinic like receptor agonist (physostigmine) and antagonist (atropine) on the acquisition of morphine-induced place preference has been investigated in male Wistar rats. For this purpose, two 22 gauges guide cannula...
متن کاملThe role of acetylcholine muscarinic receptors in the rat basolateral amygdala on morphine-induced place preference
Some studies have shown that acetylcholine muscarinic receptors involved in the opiate reward. In the present study, the effect of intra-basolateral amygdale (BLA) acetylcholine muscarinic like receptor agonist (physostigmine) and antagonist (atropine) on the acquisition of morphine-induced place preference has been investigated in male Wistar rats. For this purpose, two 22 gauges guide cannula...
متن کاملMuscarinic acetylcholine receptors in the lung.
5 genetically distinct subtypes of muscarinic acetylcholine receptors have been cloned from human and rat tissues [l, 2 , 31 and these have been dubbed ml, m2, m3, m4 and m5. Each individual subtype has been expressed in animal cells and their pharmacology determined (4). It appears that the pharmacological subtypes Ml, M2 and M3 correspond to the cloned subtypes ml, m2 and m3. However, m4 and ...
متن کاملMuscarinic acetylcholine receptors of the developing retina.
Six- and 13-day chicken embryo retinas contain 10 and 320 fmol per mg of protein of specific binding sites for 3-[3H]quinuclidinyl benzilate, a ligand of muscarinic acetylcholine receptors. Most of the receptors of 13-day embryo retina were found, by autoradiography, to be localized in two sharp bands within the inner synaptic layer of the retina. In the adult, the receptors were found almost e...
متن کاملMuscarinic acetylcholine receptors in developing chick heart.
The chronotropic response of embryonic chick hearts to cholinergic agents is first clearly detectable on day 5 in ouo and full responsiveness develops by day 7. Muscarinic acetylcholine receptors in fully responsive 9day-old hearts specifically bind the muscarinic antagonist quinuclidinyl benzilate. Binding is blocked effectively by muscarinic agonists and antagonists but is poorly inhibited by...
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ژورنال
عنوان ژورنال: eneuro
سال: 2018
ISSN: 2373-2822
DOI: 10.1523/eneuro.0340-18.2018